A preexisting dermatosis is the cause of exfoliative dermatitis in twothirds of cases, including psoriasis, atopic dermatitis, contact dermatitis, pityriasis rubra pilaris, and seborrheic dermatitis. Related information on causes of exfoliative dermatitis. As with all medical conditions, there may be many causal factors. Exfoliative dermatitis is a rare condition that affects % of the entire population.
It is characterized by redness and scaling of the skin that begins in. Nine patients with chronic exfoliative dermatitis were studied in order to delineate the problem of folate loss and absorption in this condition. Then the skin becomes scaly, thickened, and sometimes crusted. Exfoliative dermatitis at a glance exfoliative dermatitis ed is defined as diffuse erythema and scaling of the skin involving more than 90% of the total body skin surface area. Folate losses from the skin in exfoliative dermatitis. Exfoliative dermatitis causes, prevention, symptoms. It is often accompanied by, itching, skin redness, and hair loss. Exfoliative dermatitis article about exfoliative dermatitis. An allergic reaction causes irritation of the skin, which can occur in various forms, including active blistering and flaking.
Read more about symptoms, diagnosis, treatment, complications, causes and prognosis. We strongly recommend that you talk with a trusted. See full list of 10 medications causing exfoliative dermatitis. Exfoliative dermatitis is widespread erythema and scaling of the skin caused by preexisting skin disorders, drugs, cancer, or unknown causes. Exfoliative keratolysis treatment, cure, symptoms, causes. Jun 22, 2019 admin june 22, 2019 june 22, 2019 no comments on eritrodermia exfoliativa pdf english translation, synonyms, definitions and usage examples of spanish word eritrodermia exfoliativa. In particular, drug induced exfoliative dermatitis ed are a group of rare and more severe drug hypersensitivity reactions dhr involving skin and mucous membranes and usually occurring from days to several weeks after drug exposure. Dr amanda oakley, dermatologist, hamilton, new zealand, 1999. It is known to affect people of all races and countries. Below is the list of complications and problems that may arise if exfoliative dermatitis is left untreated.
Exfoliative keratolysis is a condition of hands and feet, belonging to a group of skin disorders called dermatitis. Erythroderma is an inflammatory skin disease with redness and scaling that affects nearly the entire cutaneous surface. Exfoliative dermatitis of this etiology is usually difficult. Generalized exfoliative dermatitis is a severe inflammation of the entire skin surface due to a reaction to certain drugs, a preexisting skin condition and sometimes cancer. In approximately 25% of people, there is no identifiable cause. Exfoliative dermatitis is a condition which causes exfoliation and redness of the skin. Exfoliative dermatitis pictures, images and stock photos. Erythroderma is widespread scaling, peeling, and flaking of the skin. Systemic and potentially lifethreatening complications include fluid and electrolyte imbalance, thermoregulatory disturbance, fever, tachycardia, highoutput failure, hypoalbuminemia, and septicemia. Keratolysis exfoliativa is a common skin condition in which there is focal peeling of the palms and less often the soles. State of the art article pdf available in clinical and molecular allergy 141 december 2016 with 1,369 reads how we measure reads. It often precedes or is associated with exfoliation skin peeling off in scales or layers, when it may also be known as exfoliative dermatitis ed.
Drug eruption is a common cause of exfoliative dermatitis, so a thorough medication history is essential. Exfoliative dermatitis following penicillin therapy annals. Erythroderma is generalized exfoliative dermatitis, which involves 90% or more of the. Exfoliative dermatitis in a cat university of illinois. Certain lymphomas cancers of the lymph nodes and other cancers, such as leukemia, may also cause exfoliative dermatitis. Search from 60 top exfoliative dermatitis pictures and royaltyfree images from istock. Exfoliative dermatitis may start rapidly or slowly. The diagnosis of exfoliative dermatitis is based on skin findings on physical examination and not on the underlying etiology for the dermatitis, which is variable and may be idiopathic see differential diagnosis. Low serum folate activity was found in six patients. Erythroderma is the term used to describe intense and usually widespread reddening of the skin due to inflammatory skin disease. People who are more than 40 years of age have a greater risk of developing this disorder. The lip may look normal or red before the formation of the thickened surface layer. Erythema multiforme em, stevensjohnson syndrome sjs and toxic epidermal necrolysis ten are the main clinical presentations of drug induced ed. The folate content of exfoliated skin was compared with values obtained from normal skin, and a four to sixfold increase was observed.
The term dermatitis describes an inflammatory response of the skin, caused by contact with allergens or irritants, exposure to sunlight, or by poor circulation, even stress. Full text full text is available as a scanned copy of the original print version. Erythroderma and exfoliative dermatitis clinics in dermatology. Exfoliative dermatitis ed is defined as diffuse erythema and scaling of the skin involving more than 90% of the total body skin surface area. Further relevant information on causes of exfoliative dermatitis may be found in. In about one fifth of the patients the exfoliative dermatitis was associated with mycosis fungoides and lymphomas. Folate losses from the skin in exfoliative dermatitis jama. Five cases of exfoliative dermatitis in cats were presented from 1996 to 2002 in which a feline.
Pdf a prospective study in 80 exfoliative dermatitis patients over a period of 5 years establishes 41. In approximately 25 percent of people, there is no identifiable cause. Exfoliative dermatitis msd manual professional edition. Exfoliative dermatitis, sometimes called erythroderma, is serious but fairly uncommon. In some cases, it is a complication of other skin diseases, such as atopic dermatitis, psoriasis, and contact dermatitis. What is exfoliative dermatitis and how to deal with it. More rarely, it may be indicative of a systemic disease, such as cancer of the lymphoid tissue. The top layer of skin, the epidermis, falls off over large parts of the body. Erythroderma or exfoliative dermatitis is caused by various diseases including eczema of various subtypes, psoriasis, lymphoma, leukaemia, pemphigus foliaceus, lichen planus, dermatophytosis, crusted scabies, drugs including phenylbutazone, phenytoin, carbamazepine, gold salts, lithium, cimetidine, hereditary disorder like ichthyosiform erythroderma and pityriasis rubra pilaris also can lead.
Get a printable copy pdf file of the complete article 409k, or click on a page image below to browse page by page. The peeling and scaling will also be known as sloughing. Erythroderma can be defined as diffuse inflammation of all or most of the skin that cannot be immediately classified as some other specific disease process. Several large studies have reported a widely varied incidence of exfoliative dermatitis ed ranging from 0.
The most common cause of exfoliative dermatitis is generalization of a preexisting dermatitis. Severe allergy contributes to the fact that in contact with the allergen varying degrees of exfoliation, including necrotic dermatitis develops. Erythroderma describes generalized redness and scaling of the skin of more than 30% bsa. Possible causes include other underlying skin conditions, medications, malignancy or undeterminable factors.
Exfoliative dermatitis definition of exfoliative dermatitis. The condition has been associated with thymomas but has been described without a thymoma. Exfoliative dermatitis merck manuals professional edition. The most common cause of erythroderma is exacerbation of an underlying skin disease, such as psoriasis, contact dermatitis, seborrheic dermatitis, lichen planus, pityriasis rubra pilaris or a drug reaction, such as the use of topical steroids.
Generalized exfoliative dermatitis, or erythroderma, is a severe inflammation of the entire skin surface. Exfoliative dermatitis is an extreme state of skin irritation resulting in extensive erythema andor scaling of the body. Aug 22, 2016 drug induced exfoliative dermatitis ed are a group of rare and severe drug hypersensitivity reactions dhr involving skin and usually occurring from days to several weeks after drug exposure. Cutaneous drug eruptions are one of the most common types of adverse reaction to medications, with an overall incidence of 23 % in hospitalized patients. Exfoliative dermatitis information mount sinai new york.
The commonest causes of acute erythroderma are psoriasis, atopic and other varieties of eczema, cutaneous tcell lymphoma and drug reactions. Exfoliative dermatitis, or erythroderma, is an erythematous, scaly dermatitis involving at least 90% of the skin surface. Get a printable copy pdf file of the complete article 275k, or click on a page image below to browse page by page. Aug 15, 2019 exfoliative dermatitis, or erythroderma, is an erythematous, scaly dermatitis involving at least 90% of the skin surface. Symptoms and signs are pruritus, diffuse erythema, and epidermal sloughing. An example of atopic dermatitis is eczema, an itchy rash that produces redness, blisters and scaling. Exfoliative definition of exfoliative by the free dictionary. Yes, exfoliative dermatitis causes complications if it is not treated. The icd10cm code l26 might also be used to specify conditions or terms like chronic generalized exfoliative dermatitis, diffuse dermatitis, diffuse dermatitis, druginduced desquamation of skin, exfoliative disorder of skin of scalp, generalized exfoliative contact dermatitis, etc. Exfoliative dermatitis msd manual consumer version. Erythroderma is generalized exfoliative dermatitis, which involves 90% or more of the patients skin. Generalized exfoliative dermatitis johns hopkins medicine. Exfoliative dermatitis occurs in all races and ethnic groups, with men being affected more than women maletofemale ratio varies between 2.
Given the results of the workup and clinical response, the presenting rash is most consistent with erythroderma syndrome or exfoliative dermatitis. It is also known as exfoliative keratolysis, dyshidrosis lamellosa sicca, and focal palmar peeling. Systemic and potentially lifethreatening complications include fluid and electrolyte imbalance, thermoregulatory disturbance, fever, tachycardia, highoutput failure. Methods medical records from patients with diagnosis of exfoliative dermatitis seen at the hospital. Exfoliative dermatitis is known to develop in people having severe cases of psoriasis or eczema.
This inflammation may include the perioral skin the skin around the mouth, the vermilion border, or the labial mucosa. Nov 01, 2012 exfoliative dermatitis is an extensive scaling of the skin, frequently associated with pruritus or itching, erythroderma or redness of the skin, and loss of hair. Therefore, patients should be queried about a history of psoriasis or atopic, contact, seborrheic, or chronic actinic dermatitis. Exfoliative dermatitis causes, symptoms, risk factors. Treatment involves corticosteroids and correction of the cause. Exfoliative cheilitis presents with continuous peeling of the vermilion outer part of the lips. By and large, most cases involve a preexisting skin disease. Find highquality stock photos that you wont find anywhere else. The main characteristics of this disease is patchy peeling of the skin from palms, soles or both 1. Links to pubmed are also available for selected references. Exfoliative dermatitis tends to involve most, if not all, of the skin. Journal of feline medicine and surgery 16, 10201023 forstervan hijfte m.
The skin and the vermilion border are more commonly involved, as the mucosa is less affected by inflammatory and allergic reactions. This term applies when 90% or more of the skin is affected. This is due to a reaction to certain medicines, a preexisting skin condition, and sometimes cancer. Complications can include infection, loss of nutrients, dehydration, and heart failure, rarely leading to death. For example, gentle skin care is key to preventing exfoliative dermatitis flareups in atopic. Among 5 patients with exfoliative dermatitis, the most common causative factors were drugs and preexisting dermatoses. At first the entire skin surface becomes red and shiny. Idiopathic erythroderma is sometimes called the red man syndrome. Aug 15, 2019 the most common cause of exfoliative dermatitis is generalization of a preexisting dermatitis.
Exfoliative dermatitis is a disease process in which most, and sometimes all, of the skin is involved in erythematous inflammation resulting in massive scaling. The root cause of exfoliative dermatitis is a disorder of your skin cells. Erythroderma and exfoliative dermatitis springerlink. Instances of idiopathic exfoliative dermatitis probably represent examples in which the cause was overlooked. The peeling appears to be cyclical and proceeds at different rates in different sites, so there is always some part. Exfoliative dermatitis also known as erythroderma, is an uncommon but serious skin disorder characterized by widespread redness erythema, peeling, flaking and scaling of the skin caused by preexisting skin disorders, drugs, cancer, or unknown causes. The skin and the vermilion border are more commonly involved, as the mucosa is less affected by inflammatory and allergic reactions it is a general term, and there are many recognized types and different causes. Exfoliative dermatitis merck manuals consumer version. Objective to report the frequency of clinical features and causes associated with exfoliative dermatitis in patients seen at the dermatology section of the. Prevention of exfoliative dermatitis ed depends on adequate control of underlying etiology. Exfoliative dermatitis, generalized redness and scaling of the skin that usually arises as a complication of a preexisting skin disease or of an allergy. The rapid turnover of skin cells causes peeling and scaling of the skin.
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